Curriculum Vitae (CV)
Specialty :
Obstetrics & Gynecology & Endocrinology
Education:
Graduated from School of Medicine, University of Chiba, March in 1961
Internship: Toranomon Hospital
M.D., NO. 179295 in June 14, 1962
Ph.D., Dept. of Obstetrics & Gynecology, School of Medicine, University of Tokyo in November 10 in 1969
Academic Appointment and Professional Experience
2015.8 －2018,7
2015.8 －2018..7
2013.1 －2015.7
2007.11－2011.9
2007.3 －2008.12
2005.9 －2011.9
2004.2 －2009.4
2002.6 －2006.4
2002.7 －2007.6
2000.2 －present
1996.7 －2000.1
1997.4 －1999.3
1994.7 －1996.4
1991.5 －1994.6
1985.8 －1991.4
1980.7 －1985.7
1976.10－1980.6
1976.10 - 1980,8
1974.7 －1976.9
1971.7 －1974.6
1970.7 －1971.6
1968.11－1970.6
1966.6 －1968.10
1962.4 －1966.5
Regular staff ~
Regular medical staff in Clinical Research Tokyo Hospital
Chairman of Central IRB/ERB in Clinical Research Tokyo Hospital
Consultant,I'rom Holdings Co.,Ltd.
COO,I'cros Co.,Ltd.
Medical Adviser,I'rom Co.,Ltd.
President,GMS-Corporation
President,HiMedic Co.,Ltd. Tokyo,Japan
Business Adviser,Takamatsu Cluster (MEXT)in Kagawa supported by the Japan Government
President,Waki-Corporation,Tokyo,Japan
Executive Vice President / Medical Director,Mediscience Planning Inc.,Tokyo,Japan
Visiting Faculty,Postgraduate School of Pharmacy,University of Chiba,Chiba,Japan
Medical Manager of Research & Development Dept.,Upjohn Pharmaceuticals Ltd.in Japan
Director,Senior General Manager of Clinical Development and Medical Affairs,ZENECA
K.K (ICI),Osaka,Japan.
Vice President of Sekishindo Hospital,Kawagoe,Saitama,Japan
Head of Dept. of Obstetrics & Gynecology (Colonel),Self-defense Forces Central
Hospital / Mishuku Hospital,Tokyo,Japan Faculty,Advanced Nursing School of Self-
defense Forces Central Hospital
Visiting Faculty,Mid-wife School,School of Medicine,University of Tokyo, Tokyo,Japan
Head of Dept. of Obstetrics & Gynecology,National Medical
Center Hospital,Tokyo, Japan Faculty of Advanced School of Nursing,National Medical
Center Hospital Visiting Scientist of National~ Nutritional Research Institute,Tokyo,Japan
Head of Obst. & Gyne. ~ Tokyo, Japan.
Faculty of Advance School of Nursing, National Medical Center Hospital
Visiting Scientist of ~ Tokyo, Japan.
Associate Professor,Dept. of Obstetrics & Gynecology,University of Washington,School of Medicine,Seattle,Washington,U.S.A.
Assistant Professor,Dept. of Obstetrics & Gynecology,University of Washington,School of
Medicine,Seattle,Washington,U.S.A.
Senior Fellow,Dept. of Obstetrics & Gynecology,University of Washington,School of
Medicine,Seattle,Washington,U.S.A.
Clinical Head of Obstetrics &Gynecology,SanrakuHospital
(Affiliateto theUniversity of Tokyo), Tokyo,Japan
Research Associate,Dept. of Medicine,Montefiore Hospital,University of Pittsburgh,
Pittsburgh,Pennsylvania,U.S.A.
Fellow,Dept. of Obstetrics & Gynecology,University of Tokyo,Tokyo,Japan
Present/Past Membership of Scientific or Professional Societies
Academic Societies/ Scientific Association
Japanese Society of Obstetricians and Gynecologists, Japanese Society of Urology, The Japanese Endocrine
Society, The American Endocrine Society, The Japanese Society of Chemotherapy, Japanese Society of
Clinical Pharmacology and Therapeutics, Japanese Association of Pharmaceutical Medicine (JAPhMed),
Drug Information Association (DIA).
Main Research and Medical Topics
1) Biosynthesis and metabolism of estrogens in feto-maternal-placental unit
2) Clinical study of placental sulfatase deficiency
3) Sexual differentiation of hepatic drug-metabolizing enzyme particularly for dehydroepiandrosterone in mammals
4) Inhibin and relaxine during human pregnancy
5) Biochemistry and role of sex-steroid binding protein (globulin)
6) Prophylaxis(Prophylactic effect of antibiotics)for postoperative infections in gynecological -
obstetrical surgery using febrile morbidity,fever index and infection rates
7) Clinical development of new drugs
Research Studies
Presentation in scientific Meetings 89
Publication 112 ( English 33, Japanese 79 )
Bookｓ＆Summery Reports 15
Main Published Papers in English
1. Nakayama,T.,Arai,K.,Satoh,K.,Nagatomi,K.,Tabei,T. and Yanaihara,T.: The formation of estriol from
estradiol-17B by the human fetal adrenal tissue. Endocrinologica Japonica 13: 153-159,1966.
2. Nakayama,T.,Arai,K.,Yanaihara,T.,Tabei,T.,Satoh,K. and Nagatomi,K.: Oestrogen metabolism in
anencephalus. Acta Endocrinologica 55: 369-377,1967.
3. Nakayama,T.,Arai,K.,Tabei,T.,Yanaihara,T.,Satoh,K. and Nagatomi,K.: Biosynthesis of estrogens in
in vitro rfusion of the human placenta. Endocrinologica Japonica 14T251-258,1967.
4. Nakayama,T.,Arai,K.,Nagatomi,K.,Tabei,T.,Yanaihara,T. and Fujita,Y.: Biosynthesis of estrogens by
the perfused human ovary. I. Conversion of progesterone-l4C and androst-4-ene-3,17-dione-14C to
estradiol-17β. Endocrinologia Japnonica 14: 259-264,1967.
5. Nakayama,T.,Arai,K.,Yanaihara,T.,Satoh,K.,Nagatomi,L.,Tabei,T. and Fujita,Y.: Formation of
estrogens in the feto-placental compartments. Endocrinologica Japonica 15: 135-143,1968.
6. Tabei,T.: Biosynthesis of estrogens in the human placenta. (Thesis presented to the Department of
Obstetrics and Gynecology,University of Tokyo). Acta Obstetrica et Gynaecologica Japonica 17: 1-10,
1970
7. Tabei,T. and Heinrichs,W.L.: Enzymatic oxidation and reduction of C19-5-3β-hydroxysteroids by
hepatic microsomes. 1. Biosynthesis of 3β,17β-dihydroxyandrost-5-en-16-one and sex differences in
adult rats. Endocrinology 91: 969-976,1972.
8. Tabei,T. and Heinrichs,W.L.: Enzymatic oxidation and reduction of C19-Δ5-3β-hydroxysteroids by
hepatic microsomes. II. Effect of age in rats on 16,17-oxidoreduction of 3β-hydroxyandrost-5-en-17-
one (DHA). Endocrinology 92: 1161-1164,1973.
9. Herrmann,W.L.,Heinrichs,W.L. and Tabei,T.: Peripheral control of hormone metabolism. Am. J. Ob.
Gynec. 117: 679-688,1973.
10. Tabei,T. and Heinrichs,W.L.: Neonatal Differentiation of hepatic 16αand 7α-hydroxylases. Gynec.
Invest. 4: 229-236,1973.
11. Tabei,T. and Heinrichs,W.L.: Enzymatic oxidation and reduction of C19-Δ5-3β-hydroxysteroids by
hepatic microsomes. Ⅲ. Critical period for the neonatal differentiation of certain mixed-function
oxidases. Endocrinology 94: 97-103,1974.
12. Tabei,T. and Heinrichs,W.L.: Biosynthesis of 3β,17β-dihydroxyandrost-5-en-16-one by hepatic
microsomes from previable and anencephalic human fetuses. Acta. Endocrinologica 76: 576-582,
1974.
13. Tabei,T.,Haga,H.,Heinrichs,W.L. and Herrmann,W.L.: Metabolism of progesterone by rat brain,
pituitary gland and other tissues. Steroids 23: 5,651-666,1974.
14. Tabei,T. and Heinrichs,W.L.: Metabolism of progesterone by the brain and pituitary gland of
subhuman primates. Neuroendocrinology 15: 281-289,1974.
15. Tabei,T.,Fukushima,K. and Heinrichs,W.L.: Enzymatic oxidation and reduction of Cl9-Δ5-3β-
hydroxysteroids by hepatic microsomes. IV. Induction of DHA hydroxylase and aminopyrine N-
demethylase in immature rats by androgens. Endocrinology 96: 815-819,1975
16. Tabei,T. and Troen,P.: Formation of 6-hydroxylated progesterone in human placenta and response to
HCG. J. Clin. Endocrinol. Metab. 40:497,1975.
17. Tabei,T.and Heinrichs,W.L.: Enzymatic oxidation and reduction of Cl9-Δ5-3βhydroxysteroids by
hepatic microsomes. V. Testosterone as a perinatal determinant in rats of 16,17-oxido-reduction of
3β-hydroxandrost-5-en-17-one (DHA). Endocrinology 97: 418-424,1975.
18. Tabei,T. and Heinrichs,W.L.: Diagnosis of placental sulfatase deficiency. Am. J. Ob. Gynec. 124:
409-414,1976.
19. Tabei,T. and Heinrichs,W.L.: Hepatic steroid hydroxylase and aminopyrine N-demethylase activities in
pregnant rats and rabbits and the effect of phenobarbital. Biochem. Pharma. 25: 2099-2101,1976.
20. Tabei,T. and Heinrichs,W.L.: Neonatal effect of clomiphene and o,p'-DDT on hepatic oxidative
metabolism of male rats. Hormone Research,7: 227-231,1976.
21. Burry,K.,Tabei,T.,Petra,P.,Schiller,H.,Resko. J and Heinrichs,W.L.: Differentiation of androgen
dynamics in rhesus monkeys. Gynecol. Invest. 2:52- ,1976.
22. Tabei,T.,Mickelson,K.,Neuhans,S. and Petra,P.: Sex-steroid binding protein (SBP)in dogs. J. Steroid
Biochem. 9: 983-988,1978.
23. Wagatsuma,T.,Tabei. T.,Tabuchi,T.,Kaku,R.,Fukuoka,H. and Sakamoto,S.: Copper as antifertility
agent in intrauterine devices. Acta and. Gynec. JPN 31: 1353-1357,1979.
24. Wagatsuma,T.,Tabuchi,T.,Tabei,T. and Kaku,R.: Interruption of pregnancy with vaginal suppositories
containing 16,16-dimethyl-trans-Δ2-prostaglandin E1 methyl. Contraception 19: S97-604,1979.
25. Heinrichs,W.L.,Tabei,T.,Kuwabara,Y.,Burry,K.,Resko,J.,Petra,J.,Shiller,H. and Namkung,P.:
Differentiation and regulation of peripheral androgen metabolism in rats and rhesus monkeys. Am. J.
Obst. Gynec. 135: 974-983,1979.
26. Burry,K.,Tabei,T.,Resko,J.,Petra,P.H. and Heinrichs,W.L.: Differentiation of sex-steroid binding
protein (SBP)in adult rhesus monkeys,Am. J. Obst. Gynec. 136(4): 446-450,1980.
27. Vidgoff,J.,Buxman,M.,Shapiro,L.J.,Diamond,R.L.,Tabei,T. and Heinrichs,W.L.: Placental steroid
sulfatase deficiency: association with arylsulfatase A deficiency. Am. J. Human Genetics 34(3):
434-443,1982.
28. Seki,K.,Uesato,T.,Kato,K. and Tabei,T.: The secretory patterns of relaxin and human chronic
gonadotropin in human pregnancy. Endocrinologica Jap. 32(5)741-744,1985.
29. Seki,K.,Uesato,T.,Tabei,T. and Kato,K.: Serum relaxin in patients with hydatidiform mole. Obst. &
Gynec. 67(3): 381-383,1986.
30. Seki,K.,Uesato,T.,Kato,K. and Tabei,T.: Decline of serum relaxin levels before labor in women. Act.
Obst. & Gynec. JPN 39: 2073:74,1987.
31. Seki,K.,Kato,K. and Tabei,T.: Serum immunoactive relaxin in women during a 24-h period. J. Reprod.
Fertility 79(2): 363-365,1987.
32. Seki,K.,Uesato,T.,Tabei,T. and Kato,K.: Serum relaxin and steroid hormones in spontaneous
abortions. Acta. Obstet. Gynecol. Scand. 67: 483-486,1988.
33. Tabei,T.,Ochiai,K.,Terashima,Y. and Takanashi,N.: Serum levels of inhibin in maternal and umbilical
blood during pregnancy. Am. J. Obst. Gynecol. 164(3): 896-900,1991.